Remini's entrance into television came in the mid-'80s, when she got her first speaking line as an actress on an episode of Head of the Class. Later she was on the show Cheers where she appeared as Carla Tortelli's daughter Serafina on two episodes. In 1989, she played the lead on Living Dolls, a short-lived spin-off from Who's the Boss? In 1991, she had a recurring role as Stacy Carosi, a love interest of Zack Morris, on Saved by the Bell (during the summer when the gang worked at the Malibu Sands Beach Club) and starred in the short-lived sitcom The Man in the Family.
Remini also guest starred in The Commish, where her character was involved in the plot line responsible for Geoffrey Naufft's departure from the show. She gained some popularity with her role as Terri Reynolds on the 1997 NBC comedy series Fired Up. She had several guest appearances on shows such as Evening Shade, Diagnosis: Murder, NYPD Blue and Friends (in the Season 1 episode "The One with the Birth"). She has appeared on MTV Cribs. She had tried to audition for the part of Monica Geller but alas she did not get the part.